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Melatonin cannot replace sleeping pills

release time:2022-05-20|reading:

      褪黑素不能替代安眠药

      Melatonin cannot replace sleeping pills

  In previous years, 24.9% of people reported insomnia. Now, the number of people suffering from insomnia has increased to 36.1%.

  I don't know how many people say they go to bed on time, but the mobile phone screen is still open until the early morning.

  In order to improve sleep, many people choose the health care product "melatonin", and stick to the "punk health" of melatonin while staying up late.

  Is this correct?

  Melatonin can regulate sleep

  Melatonin can be divided into exogenous and endogenous according to its source.

  Endogenous melatonin plays an important role in regulating circadian rhythm and sleep.

  At night or when the light is weak, it secretes more, making people gradually fall asleep.

  Melatonin secretion is sufficient, which can make people fall asleep faster, reduce wakefulness, and sleep longer, thus improving the quality of sleep.

  During the day or when the light is sufficient, the secretion of melatonin decreases, making people stay awake.

  Most of the melatonin sold on the market is exogenous melatonin, which is mainly used for chemical synthesis. Its chemical name is N-acetyl-5-methoxytryptamine.

  In addition to the pineal gland, other parts of the body can also secrete melatonin, such as gastrointestinal mucosa, retina and bone marrow, but the amount is small.

  The secretion of melatonin in the body is regular.

  The secretion of melatonin at night is 5-10 times as much as that during the day.

  In addition, the secretion of melatonin has a great influence on the development of age.

  After 3 months of birth, the secretion system of melatonin in neonates began to increase gradually, and the secretion decreased gradually during puberty. At the age of 35. the pineal gland in the body began to shrink, at this time, the secretion of melatonin decreased significantly.

  At about 45 years old, the secretion of melatonin in the human body drops to half of that in childhood.

  By the age of 80 or so, the secretion of melatonin will drop to the lowest level.

  Long term use of melatonin is not recommended

  Melatonin can regulate one's sleep, but it is used as the raw material of health care products in China. Its efficacy is defined as improving the sleep of patients. The recommended daily dosage is 1 mg~3 mg.

  In other words, melatonin is not a drug, and it cannot replace sleeping pills to treat insomnia.

  At present, there is no clear research conclusion on the clinical application of melatonin. As an auxiliary treatment, melatonin has a certain role in promoting sleep.

  So who can use melatonin to help sleep?

  People with sleep disorders.

  Melatonin has no effect on entering sleep, only for deepening sleep, and has no positive effect on stubborn sleep disorder.

  If you need to take it, be sure to follow the instructions.

  People who need to adjust for jet lag or shift at night.

  Night shift drivers, medical management personnel and other night shift personnel or people who have just finished cross time zone flight, as well as people who cannot sleep well during the day, may consider taking melatonin.

  aged.

  The elderly have insufficient secretion of melatonin, which is easy to cause sleep disorders, so we can consider supplementing exogenous melatonin.

  The effect of melatonin weakens with the passage of time. Its half-life is relatively short and the action time is short. Therefore, taking it half an hour before going to bed has a better effect, and the melatonin sustained-release effect is better.

  Unlike sleeping pills, normal use of melatonin will not lead to drug dependence risk and hangover.

  It is worth noting that, although the safety of long-term use of melatonin has not been confirmed, long-term use of exogenous melatonin may reduce the secretion of melatonin itself, and the self secretion function can not be recovered or only partially recovered. Once dependence is formed, it will cause sleep disorder and aggravate insomnia.

  Therefore, long-term use is not recommended.

  In addition, most insomnia is not due to melatonin secretion disorder or decreased secretion.

  At this time, the use of exogenous melatonin can not improve sleep in a timely and effective manner.

  In a word, melatonin should be selected according to the doctor's advice.


Shandong Zhushi Pharmaceutical Group Co., Ltd., founded in 2003, has more than 5000 registered employees. After years of development, it has developed into a diversified industrial cluster integrating medical devices, polymers, cosmetics, health food, daily necessities and biological reagent production, enterprise management consulting and training, real estate economy, pharmaceutical transportation, pharmaceutical printing, etc.


Adhering to the concept of life, health and happiness, the Group provides you with full chain health services.






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